M6. Effectiveness of Telemedicine Interventional Management in Adult With Heart Failure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

There is growing evidence that Telemedicine Interventional Management (TIM) can be advantageous in societies with an increasing prevalence of Heart Failure (HF). The objective of this meta-analysis was to assess the effectiveness of telemedicine intervention for patients with HF compared with conventional healthcare.

We systematically searched PubMed, MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials for randomized controlled trials (RCT) from January 2010 to December 2020. The primary effectiveness outcome was all-cause mortality. Secondary outcomes were all-cause hospitalization, cardiovascular mortality, and heart failure hospitalization. We include data from 15 RCTs comprising data for 11,262 patients. Telemedicine resulted in statistically significant risk reduction of all-cause mortality (OR 0.81, 95% CI 0.72–0.91, p = 0.0004). Receiving Telemedicine interventions is likely to reduce the hospitalization for all causes (OR 0.90, 95% CI 0.83-0.98, p = 0.02, I2 = 84%) and the hospitalization due to HF (OR 0.88, 95% CI 0.72-0.99, p = 0.04, I2 = 61%), compared with interventions from conventional healthcare. OR of telemedicine cardiac mortality (OR 0.82, 95% CI 0.70-0.97, p = 0.02, I2 = 0%).

Compare with conventional healthcare, telemedicine intervention combines with medical support prove to be more effective for HF adult, particularly in reducing all-cause mortality, all-cause hospitalization, cardiovascular mortality, and heart failure hospitalization. While further research is required to confirm these findings and identify optimal telemedicine strategies and the duration of follow-up for which it confers benefits.