OR29. Echocardiography Parameters Affecting Hospitalization in Pulmonary Arterial Hypertension Patients: A Single Center Study

Pulmonary arterial hypertension (PAH) is one form of pulmonary hypertension characterized by increased of mean pulmonary arterial pressure and pulmonary vascular resistance with normal pulmonary arterial wedge pressure. Echocardiography is one of modalities to assess PAH. The aim of this study is to describe hospitalization risk based on echocardiography parameters in patients with PAH in DR. M. Djamil Hospital.

We enrolled patients with PAH who underwent echocardiography examination from January 2016 until July 2020. There were 47 patients met the inclusion criteria. Mean of age was 34±13 years old. About 68% patients were female and the most common symptom was dyspnea (92%). Congenital heart disease was the most common etiology in PAH (89%) and about 53% patients got vasodilator. Mean of systolic pulmonary artery (PA) pressure was 68±35 mmHg, tricuspid valve gradient was 60±35 mmHg, and tricuspid regurgitation velocity maximum was 3.7±1.1 m/s. Hospitalization within a year after first echocardiography is found in 21 patients (45%). By T-test analysis, we found a significant difference in mean PA pressure between hospitalized and non-hospitalized group (69 mmHg vs 24 mmHg, p = 0.000). There were no significant difference in another echocardiography parameter such as right atrial dimension, right ventricular dimension and function, estimating right atrial pressure, pericardial effusion, pulmonary acceleration time, and pulmonary artery diameter.

Higher mean PA pressure was a significant factor affecting hospitalization in PAH patients. Further study using invasive examination is needed to confirm the result.