Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference
EP Europace Journal

Abstract
The risk of developing atrial fibrillation (AF) and its complications continues to increase, despite good progress in preventing AF-related strokes.
This article summarizes the outcomes of the 7th Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA) held in Lisbon in March 2019. Sixty-five international AF specialists met to present new data and find consensus on pressing issues in AF prevention, management and future research to improve care for patients with AF and prevent AF-related complications. This article is the main outcome of an interactive, iterative discussion between breakout specialist groups and the meeting plenary. AF patients have dynamic risk profiles requiring repeated assessment and risk-based therapy stratification to optimize quality of care. Interrogation of deeply phenotyped datasets with outcomes will lead to a better understanding of the cardiac and systemic effects of AF, interacting with comorbidities and predisposing factors, enabling stratified therapy. New proposals include an algorithm for the acute management of patients with AF and heart failure, a call for a refined, data-driven assessment of stroke risk, suggestions for anticoagulation use in special populations, and a call for rhythm control therapy selection based on risk of AF recurrence.
The remaining morbidity and mortality in patients with AF needs better characterization. Likely drivers of the remaining AF-related problems are AF burden, potentially treatable by rhythm control therapy, and concomitant conditions, potentially treatable by treating these conditions. Identifying the drivers of AF-related complications holds promise for stratified therapy.
Contributors

Larissa Fabritz
Author

Harry J G M Crijns
Author

Eduard Guasch
Author

Andreas Goette
Author

Karl Georg Häusler
Author

Dipak Kotecha
Author

Thorsten Lewalter
Author

Christian Meyer
Author

Tatjana S Potpara
Author

Michiel Rienstra
Author

Renate B Schnabel
Author

Stephan Willems
Author

Guenter Breithardt
Author

A John Camm
Author

Anthony Chan
Author

Winnie Chua
Author

Mirko de Melis
Author

Christina Dimopoulou
Author

Dobromir Dobrev
Author

Christina Easter
Author

Lars Eckardt
Author

Doreen Haase
Author

Stephane Hatem
Author

Jeff S Healey
Author

Jordi Heijman
Author

Stefan H Hohnloser
Author

Thomas Huebner
Author

Bushra Saeed Ilyas
Author

Aaron Isaacs
Author

Ingo Kutschka
Author

Christophe Leclercq
Author

Gregory Y H Lip
Author

Elena Andreassi Marinelli
Author

Jose L Merino
Author

Lluís Mont
Author

Michael Nabauer
Author

Jonas Oldgren
Author

Helmut Pürerfellner
Author

Ursula Ravens
Author

Irina Savelieva
Author

Moritz F Sinner
Author

Alice Sitch
Author

Rüdiger Smolnik
Author

Jan Steffel
Author

Kenneth Stein
Author

Monika Stoll
Author

Emma Svennberg
Author

Dierk Thomas
Author

Isabelle C Van Gelder
Author

Burcu Vardar
Author

Reza Wakili
Author

Mattias Wieloch
Author

Stef Zeemering
Author

Paul D Ziegler
Author

Hein Heidbuchel
Author

Gerhard Hindricks
Author

Ulrich Schotten
Author

