Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference
EP Europace Journal

Abstract
Despite marked progress in the management of atrial fibrillation (AF), detecting AF remains difficult and AF-related complications cause unacceptable morbidity and mortality even on optimal current therapy. This document summarizes the key outcomes of the 8th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA). Eighty-three international experts met in Hamburg for 2 days in October 2021. Results of the interdisciplinary, hybrid discussions in breakout groups and the plenary based on recently published and unpublished observations are summarized in this consensus paper to support improved care for patients with AF by guiding prevention, individualized management, and research strategies. The main outcomes are (i) new evidence supports a simple, scalable, and pragmatic population-based AF screening pathway; (ii) rhythm management is evolving from therapy aimed at improving symptoms to an integrated domain in the prevention of AF-related outcomes, especially in patients with recently diagnosed AF; (iii) improved characterization of atrial cardiomyopathy may help to identify patients in need for therapy; (iv) standardized assessment of cognitive function in patients with AF could lead to improvement in patient outcomes; and (v) artificial intelligence (AI) can support all of the above aims, but requires advanced interdisciplinary knowledge and collaboration as well as a better medico-legal framework. Implementation of new evidence-based approaches to AF screening and rhythm management can improve outcomes in patients with AF. Additional benefits are possible with further efforts to identify and target atrial cardiomyopathy and cognitive impairment, which can be facilitated by AI.
Contributors

Stephan Willems
Author

Henning Witt
Author

André Ziegler
Author

Matthias Daniel Zink
Author

Elena Andreassi Marinelli
Author

Elena Arbelo
Author

Giuseppe Boriani
Author

Serge Boveda
Author

Claire M Buckley
Author

A John Camm
Author

Barbara Casadei
Author

Winnie Chua
Author

Nikolaos Dagres
Author

Mirko de Melis
Author

Lien Desteghe
Author

Søren Zöga Diederichsen
Author

David Duncker
Author

Lars Eckardt
Author

Christoph Eisert
Author

Daniel Engler
Author

Larissa Fabritz
Author

Ben Freedman
Author

Ludovic Gillet
Author

Andreas Goette
Author

Eduard Guasch
Author

Jesper Hastrup Svendsen
Author

Stéphane N Hatem
Author

Karl Georg Haeusler
Author

Jeff S Healey
Author

Hein Heidbuchel
Author

Gerhard Hindricks
Author

F D Richard Hobbs
Author

Thomas Hübner
Author

Dipak Kotecha
Author

Michael Krekler
Author

Christophe Leclercq
Author

Thorsten Lewalter
Author

Honghuang Lin
Author

Dominik Linz
Author

Gregory Y H Lip
Author

Maja Lisa Løchen
Author

Wim Lucassen
Author

Steffen Massberg
Author

Ralf Meyer
Author

Lluıs Mont
Author

Michael C Myers
Author

Lis Neubeck
Author

Teemu Niiranen
Author

Michael Oeff
Author

Jonas Oldgren
Author

Tatjana S Potpara
Author

George Psaroudakis
Author

Helmut Pürerfellner
Author

Ursula Ravens
Author

Michiel Rienstra
Author

Lena Rivard
Author

Daniel Scherr
Author

Ulrich Schotten
Author

Dipen Shah
Author

Moritz F Sinner
Author

Rüdiger Smolnik
Author

Gerhard Steinbeck
Author

Daniel Steven
Author

Emma Svennberg
Author

Dierk Thomas
Author

Mellanie True Hills
Author

Isabelle C van Gelder
Author

Burcu Vardar
Author

Elena Palà
Author

Reza Wakili
Author

Karl Wegscheider
Author

Mattias Wieloch
Author



