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Histone lactylation-mediated metabolic remodeling in vascular smooth muscle cells aggravates aortic aneurysm and dissection via promoting lactate accumulation

28 August 2026 (08:15 - 09:00)
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Congress Presentation Part of: Vascular remodelling, aneurysm, and calcification Atherosclerosis, Cerebrovascular Diseases, Aneurysm, Restenosis ESC2026 Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

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Doctor Li Wei Liu

Zhongshan Hospital Fudan University, Shanghai (China)

5 More presentations in this session

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TNF-α promotes WNT5B transcription via HuR-dependent R-loop stabilization in aortic dissection
Doctor Y. Xia (Shanghai, CN)
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OTULIN aggravate aneurysm/aortic dissection by promoting vascular smooth muscle cell phenotype switching via the DDX17 -FGF2 Axis
Miss X. Hu (Shanghai, CN)
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NRP1 interaction with AP2M1 promotes vascular calcification by driving endocytosis of PDGFRβ
Ms H. Chen (Shenzhen, CN)
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Venetoclax attenuates vascular calcification through combined senolytic activity and SOX9/LH3-mediated ECM remodeling
Doctor Q. He (Shenzhen, CN)
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Immunometabolic reprogramming of perivascular adipose tissue reveals brown adipocyte–mediated suppression of CCL8-driven vascular remodeling in abdominal aortic aneurysm
Doctor J. Uzokov (Tashkent, UZ)

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Vascular remodelling, aneurysm, and calcification

The Event

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ESC Congress 2026

28 August 2026 08:15 CET
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