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Inclisiran alleviates myocardial ischemia/reperfusion injury by blocking the HIF-1a/Myo1d-mediated M1 differentiation of macrophages

30 August 2026 (10:15 - 11:00)
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Congress Presentation Part of: Mechanisms of microvascular injury: from neutrophils to no-reflow Reperfusion and Reperfusion Injury ESC2026 Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

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Doctor Lei Guo

First Affiliated Hospital of Dalian Medical University, Dalian (China)

5 More presentations in this session

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Gliflozin therapy attenuates persistent systemic inflammation and monocyte metabolic dysfunction post-ACS: a comparative study across the CAD spectrum
Doctor A. Mroueh (Strasbourg, FR)
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Sex-dependent molecular signatures of reticulated platelets
Doctor S. Kuehne (Augsburg, DE)
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Neutrophil abundance determines microvascular obstruction in endotoxemia
Mr T. Artner (Vienna, AT)
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FORTIFY: a phase 2b randomised trial evaluating the effect of orticumab on coronary inflammation (FAI-Score) in post myocardial infarction patients selects for patients with high residual FAI-Score
Professor T. Villines (Charlottesville, US)
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Histologic characteristics potentially associated with coronary vasospasm in myocardial infarction cases without apparent epicardial coronary culprit stenosis.
Professor T. Matsuyama (Tokyo, JP)
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Mechanisms of microvascular injury: from neutrophils to no-reflow

The Event

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ESC Congress 2026

30 August 2026 10:15 CET
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