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Insulin resistance genetic susceptibility drives pulmonary arterial hypertension through monocyte metabolic reprogramming and immune dysregulation

28 August 2026 (10:15 - 11:00)
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Congress Presentation Part of: Pulmonary hypertension: pre-clinical Pathophysiology and Mechanisms ESC2026 Premium Access ESC Congress 2026 European Society of Cardiology

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Mr Shiqiang Hou

Zhongshan Hospital Fudan University, Shanghai (China)

5 More presentations in this session

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Interleukin-22–STAT3 Signaling Preserves Structural Integrity in the Pressure-Overloaded Right Ventricle
Doctor K. Shibao (Kurume, JP)
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Prophylactic ranolazine and trimetazidine attenuate right ventricular dysfunction and improve exercise capacity in experimental pulmonary hypertension
Doctor A. Oz (Istanbul, TR) Miss S. Asal (Istanbul, TR)
Abstract Slides
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Empagliflozin attenuates pulmonary vascular hemodynamic progression and improves right ventricular adaptation in overcirculation-induced pulmonary hypertension
Doctor A. Garcia-Alvarez (Barcelona, ES)
Abstract Slides
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Myo-inositol trispyrophosphate improves oxygen delivery and right ventricular function in rat pressure overload model
Doctor M. Maczewski (Warsaw, PL)
Abstract Slides
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Targeting the PSMB9–NGAL/MMP9 Axis: a novel neutrophil-driven mechanism and precision target for vascular remodeling in PAH
Associate Professor X. He (Guangzhou, CN)
Abstract Slides

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Pulmonary hypertension: pre-clinical

The Event

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ESC Congress 2026

28 August 2026 10:15 CET
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