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E3 ubiquitin ligase TRIM47 drives endothelial dysfunction in immune checkpoint inhibitor-associated myocarditis via K48-linked polyubiquitination and degradation of SCO1

28 August 2026 (08:15 - 09:00)
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Congress Presentation Part of: Immune checkpoint inhibitor cardiotoxicity: mechanisms, biomarkers, and early cardiovascular injury Cardio-Oncology ESC2026 Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

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Mr Runshan Gui

(China)

7 More presentations in this session

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Neutrophils contribute to αPD1-induced latent myocardial injury via NET/NETosis axis: exploration of potential patho-mechanism, diagnostic biomarkers and therapeutic targets in ICIs-associated myocard
Miss Y. Chen (Xiamen, CN)
Abstract Slides Video
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Assessment of coronary artery calcification progression on standard non-gated CT scans in melanoma patients treated with immune checkpoint inhibitors
Doctor N. Laachir (Leiden, NL)
Abstract Slides Video
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Real-world cardiovascular toxicity of immune checkpoint inhibitors in an asian population: insights from a nationwide taiwanese registry
Doctor K. Chen (Taipei, TW)
Abstract Slides Video
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IgG N-glycosylation as a novel biomarker for immune checkpoint inhibitor-associated myocarditis: a comparative glycomic study
Doctor J. Li (Beijing, CN)
Abstract Slides Video
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Myocardial deformation, myocardial work and vascular biomarkers for the assessement of patients treated with immune checkpoint inhibitors
Doctor K. Katogiannis (Athens, GR)
Abstract Slides Video

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Immune checkpoint inhibitor cardiotoxicity: mechanisms, biomarkers, and early cardiovascular injury

The Event

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ESC Congress 2026

28 August 2026 08:15 CET
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