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The role and mechanism of METTL14/CCN3 axis in lipoprotein (a) [Lp(a)] induced human aortic smooth muscle cell calcification

29 August 2025 (07:00 - 18:00)
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Congress Presentation Part of: Targeting lipoprotein-driven inflammation and oxidative stress in cardiovascular disease Lipids, Metabolism ESC Professional Premium Access ESC Congress 2025 European Society of Cardiology

About the speaker

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Doctor Zhi-Fan Li

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular D, Beijing (China)

7 More presentations in this session

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Autoantibodies against apolipoprotein A-1 and cadmium: possible links to cardiovascular and liver diseases across multiple models
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Electronegative H5 HDL: an apo(a)-containing HDL that damages neuronal DNA by potentially disrupting the BBB
Assistant Professor W. Hsu (Yunlin, TW)
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Eicosapentaenoic acid (EPA) inhibited lipoprotein(a) [Lp(a)] oxidation and its effects on expression of oxidative stress and pro-inflammatory proteins in endothelial cells
Doctor P. Mason (Boston, US)
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Nanoformulated omega-3 rich linseed oil reversed IL-6+TNF-a-induced M1 polarized THP-1 cells and monocytes of healthy donors and the activated monocytes of patients with coronary artery disease
Miss S. Hmadeh (Strasbourg, FR)
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Atorvastatin active metabolite inhibits oxidation of Lp(a), small dense LDL and triglyceride-rich lipoproteins compared to other statins through a free radical scavenging mechanism
Doctor P. Mason (Boston, US)
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Targeting lipoprotein-driven inflammation and oxidative stress in cardiovascular disease

The Event

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ESC Congress 2025

29 August - 1 September 2025
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