After graduation from the Geneva School of Medicine in 1998, Dr S Noble specialized in internal medicine and general cardiology at the University Hospital of Geneva. He also trained for one year in cardio-vascular surgery and subsequently in 2006 was accepted for a fellowship in interventional cardiology and structural heart disease interventions at the Montreal Heart Institute where he stayed until 2009. He was appointed senior lecturer at the University of Medicine, Geneva and is in charge of the structural programme at the University Hospital of Geneva. He is the author of more than 130 scientific publications, most of them in the field of interventions for structural heart disease.