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His main interest is the role of endothelium and hemodynamic forces in the regulation of microvessel resistance. The effect of training on the function of microvessels and the role of vasodilators produced by the endothelium. In addition, he is focusing on the cardiac and microvascular effects of exercise, mechanisms of endothelial dysfunction in various cardiovascular diseases, such as oxidative stress and vascular inflammation. His other interest is the adaptation and abnormalities of coronary and cerebral circulation in aging, in pathological conditions: hypertension, diabetes mellitus, obesity, and physical activity. Translational aspects of cardiovascular diseases.
