Dr. Michele Ciccarelli, MD, Ph.D., graduated in medicine in 2001 at the Federico II, University of Naples. He worked as postDoc and then as a faculty member at Thomas Jefferson University, Philadelphia (Center for Translational Medicine, Prof WJ Koch) studying the role of the GRKs in cardiac metabolism and insulin resistance during HF. Here, he was awarded by AHA with the postdoctoral fellowship in 2009. He returned to Italy in 2012 at the University of Salerno where he is currently Associate Professor at the Faculty of Medicine, working as both clinician and molecular cardiologist. His studies focus on the multiple roles played by GRKs in the physiopathology of cardiovascular diseases, and in particular on the part of the adrenergic system in regulating cardiac metabolism and mitochondrial function through the GRKs subcellular localization and activity.