Professor Igor Sobenin
National Medical Research Center of Cardiology, Moscow (Russian Federation)
Prof. Sobenin’s research activity is in a field of molecular and cellular mechanisms of atherosclerosis, including genetic and phenotypic markers of susceptibility; clinical, epidemiological and population studies in the field of chronic diseases with a special emphasis on atherosclerosis. Among the most notable results the following can be mentioned: the phenomenon of low density lipoprotein atherogenicity in diabetic patients; the phenomenon of multiple atherogenic modification of low density lipoprotein; the novel approaches to the development of drugs on the basis of ex vivo cell culture models; the novel algorithms of determination of cardiovascular risk on the basis of combination of genetic and phenotypic markers; an association of mutation burden of mitochondrial genome with atherosclerotic lesions in situ and predisposition to atherosclerosis in vivo; the method of determination of individual genetic predisposal to atherosclerosis and other chronic non-infectious diseases.
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