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Doctor Maria Carolina Guido

Heart Institute of the University of Sao Paulo (InCor), Sao Paulo (Brazil)

Member of:

European Society of Cardiology

Maria Carolina Guido obtained her Ph.D. in Science at Faculty of Medicine from University of Sao Paulo in Brazil. During her post doctorate fellowships in Vascular Biology Laboratory at University of Sao Paulo and at School of Medical Sciences of University of Campinas, she has investigated respectively the cardiac remodeling after myocardial infarction and aortic phenotype in Marfan syndrome. Awarded twice at Brazilian Congress of Cardiology & Atherosclerosis and at Meeting of Free Radicals, she currently conducts her research line at Lipids and Metabolism Laboratory of Heart Institute from University of Sao Paulo. The topics of scientific interest involve lipid metabolism, particularly in the use of drug delivery nanoparticles for the treatment of cardiovascular disease, such as, Marfan syndrome, Takotusubo cardiomyopathy, atherosclerosis, systemic arterial hypertension and septic shock.

Presentations

Methotrexate associated with a lipid core nanoparticle prevented the dilation and dissection of the aortic arch in mice with Marfan syndrome

Event: ESC Congress 2020

Topic: Vascular Diseases

Session: Basic Science Vascular ePosters

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Methotrexate reduces cardiac remodeling and improves left ventricle function in rats with Takotsubo cardiomyopathy

Event: ESC Congress 2019

Topic: Cardiomyopathies

Session: Molecular mechanisms of cardiovascular inflammation

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Losartan diminishes the expression of TGF-beta and improves cardiomyopathy in mice with Marfan syndrome

Event: ESC Congress 2019

Topic: Cardiomyopathies

Session: IPS disease modelling and congenital heart disease

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