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Doctor Michael Zile

Medical University of South Carolina, Charleston (United States of America)
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Biography
Dr. Zile is currently the Charles Ezra Daniel Professor of Medicine and Distinguished University Professor at the Medical University of South Carolina. He is a member of the Cardiology Division at the Ralph H. Johnson Department of Veteran's Affairs Health Care System in Charleston. He is the 2019 William S. Middleton Awardee for Outstanding Achievement in Biomedical Research and the 2020 South Carolina Governor’s Awardee for Excellence in Scientific Research. Dr. Zile's research career has focused on basic, translational and clinical research examining the mechanisms underlying the development and progression of heart failure; and determining how these mechanisms can be used to develop effective diagnostic, prognostic and treatment methods for Heart Failure, particularly heart failure with a preserved ejection fraction (HFpEF). Dr. Zile’s research has been funded for over 40 years by the NHLBI, VA, DOD, AHA, and industry and been summarized in more than 450 peer-reviewed publications.
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Contributor content

Mechanistic basis for differential effects of interatrial shunt treatment in HFrEF vs HFpEF
Presentation
Mechanistic basis for differential effects of interatrial shunt treatment in HFrEF vs HFpEF
RELIEVE-HF Trial Mechanisms for Differential Clinical Outcomes
Presentation
RELIEVE-HF Trial Mechanisms for Differential Clinical Outcomes
BeAT-HF: long-term safety profile and outcomes
Presentation
BeAT-HF: long-term safety profile and outcomes
Insights into the Effects of the COVID-19 Pandemic: Comprehensive Analysis from the GUIDE-HF Trial
Presentation
Insights into the Effects of the COVID-19 Pandemic: Comprehensive Analysis from the GUIDE-HF Trial
Overview of neuromodulation devices in HFrEF.
Presentation
Overview of neuromodulation devices in HFrEF.
Fibrosis is the bad guy
Presentation
Fibrosis is the bad guy
Effect of sacubitril/valsartan on plasma biomarkers that reflect extracellular matrix regulatory mechanisms and collagen synthesis in patients with heart failure and reduced ejection fraction.
Presentation
Effect of sacubitril/valsartan on plasma biomarkers that reflect extracellular matrix regulatory mechanisms and collagen synthesis in patients with heart failure and reduced ejection fraction.

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