Doctor Panagiota Efstathia Nikolaou
Academy of Athens Biomedical Research Foundation, Athens (Greece)
Biography
Panagiota-Efstathia (Naya) Nikolaou is an Assistant Professor at the Department of Health Sciences, School of Life and Health Sciences, University of Nicosia – Athens Branch, and a basic and translational researcher at the Laboratory of Heart and Vessels, Biomedical Research Foundation of the Academy of Athens (BRFAA). A Pharmacist by training, she holds an MSc and PhD in Cardiovascular Pharmacology from the National and Kapodistrian University of Athens (NKUA). Her research focuses on cardiovascular pharmacology, cardioprotection, heart failure, and endothelial dysfunction, with particular emphasis on immune–cardiac crosstalk and immunometabolic mechanisms in cardiovascular disease. She has extensive international research experience and has authored more than 40 peer-reviewed publications. She is a Core Group member of the Scientists of Tomorrow of the European Society of Cardiology (ESC) and actively contributes to international research networks and collaborations.
Contributor content
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Empagliflozin treatment pre- and post- acute myocardial infarction reduces no-reflow, inflammatory cell infiltration and infarct size while preserving cardiac function.
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Discovery and in vivo evaluation of novel inhibitors of the hydrolytic activity of mitochondrial F1Fo ATP synthase to alleviate myocardial ischemia reperfusion injury
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Empagliflozin restores the deregulated cardiac endothelial cell transcriptome in vivo upon myocardial ischemia reperfusion injury and reduces the infiltration of immune cells.
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Cardiotoxicity in light chain amyloidosis: Insights from the first murine model with intramyocardial injection of patient-derived amyloidogenic light chains
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Cardioprotection by selective SGLT2 inhibitors in a non-diabetic mouse model of myocardial ischemia/reperfusion injury: a class or a drug effect?
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Understanding the molecular mosaic of cardiotoxicity of light chains in plasma cell dyscrasias and cardiac light chain amyloidosis with the use of patient derived full-length light chains
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Empagliflozin rescues primary murine cardiac fibroblasts, but not cardiomyocytes, from hypoxia-reoxygenation injury through STAT3-mediated cascades.
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Al amyloidosis with cardiac involvement: cardiotoxicity of aggregation prone peptides deriving from variable domains of immunoglobulin light chains
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Hydrolytic activity of mitochondrial F1Fo ATP synthase as a target for myocardial ischemia: discovery and in vitro evaluation of novel inhibitors
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