Doctor James Sheppard

I am a Population Health Scientist interested in better understanding the benefits and harms of treatments, with a particular focus on cardiovascular disease prevention. My research aims to develop tools which improve the targeting of preventative therapies such as antihypertensives and statins at patients with the most to gain. I lead the Stratified Treatments Research Group at the Nuffield Department of Primary Care Health Sciences at the University of Oxford. My group is interested in developing prognostic models for treatment harms using data from large electronic health record databases. In addition I am interested in developing new strategies to deal with polypharmacy and currently lead a randomised controlled trial of antihypertensive deprescribing in patients over the age of 80 years.