Professor Valerie Schini-Kerth
INSERM, University of Strasbourg, CRBS, Strasbourg (France)
Membership:
FESC Member
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Biography
Valérie Schini-Kerth received her PhD in 1988 at the University Louis Pasteur of Strasbourg, France. She is Professor of Pharmacology at the Faculty of Pharmacy of Strasbourg University since 2000. Since 2024, she is the director of the Translational Cardiovascular Medicine research department. Her major interest is focusing on the pivotal role of the endothelium in the control of vascular homeostasis in health and disease. In particular, she is studying the mechanisms contributing to the induction of endothelial dysfunction related to ageing and major cardiovascular risk factors including hypertension and diabetes with a strong translational approach. Her recent interest is focusing on the role of premature endothelial senescence in the initiation of endothelial dysfunction and its pharmacological inhibition by drugs. She is currently the Chair of the Natural Products Section of the International Union of Basic and Clinical Pharmacology (IUPHAR).
Contributor content
Presentation
Reversal of age-related diastolic dysfunction by micronized purified flavonoid fraction in rats with attenuation of low-grade inflammation, eNOS-NO/ROS imbalance, and left ventricular fibrosis
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Sodium-glucose co-transporter 1 and 2 expression in the mammary artery of patients with bypass surgery: role of the pro-inflammatory response and contribution to oxidative stress
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Cardiac diastolic dysfunction in angiotensin II-treated hypertensive rats is associated with endothelial upregulation of SGLT1/2 in the macro and microcirculation: Protective effect of empagliflozin
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Empagliflozin treatment does not affect the hypertensive response to Ang II administration to rats but decreases oxidative stress in the arterial wall, and endothelial and cardiac dysfunction
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Coated EPA:DHA 6:1 nanoparticles cause greater endothelium-dependent relaxations of coronary artery rings than the native form: role of NO, endothelium-dependent hyperpolarization and prostanoids
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Oral intake of EPA:DHA 6:1 improves ageing-related blunted endothelium-dependent relaxations and increased contractile responses in the mesenteric artery: role of oxidative stress and cyclooxygenases
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