Prof. Iacopo Olivotto is Head of the Cardiology Unit at Meyer University Children Hospital, Head of the Cardiomyopathy Service at Careggi University Hospital, and Professor of Cardiovascular Medicine at the University of Florence, Italy. Over the last two decades, his main clinical and research interests have included various aspects of cardiomyopathies, with special focus on the translational investigation of hypertrophic cardiomyopathy. Prof. Olivotto has pioneered the design and execution of randomized clinical trials in genetic cardiomyopathies, including the seminal Explorer HCM (as the lead authors) and Sequoia HCM trials involving cardiac myosin inhibitors for symptomatic obstructive hypertrophic cardiomyopathies. He has co-authored over 400 papers in international, peer-reviewed journals. Prof. Olivotto is a co-founder of The Sarcomeric Human Cardiomyopathy Registry (Share), ICON (International CardiomyOpathy Network), and the Hypertrophic Cardiomyopathy Medical Association.