Associate Professor Toshiyuki Nagai

Currently, I lead a clinical heart failure research group whose work centers largely on clarifying the mechanisms of myocardial disease as well as proceeding outcome research. Projects cover a wide range of heart failure aspects and while my predominant focus is on the use of reginal / international heart failure registries, hemodynamic data, multimodality imaging and pathohistological data. Examples of areas include: 1) Heart failure: phenotyping in secondary care, developing precision medicine platform using registries and novel technologies (e.g., biomarkers, omics, genome, artificial intelligence). Invasive hemodynamic assessment using exercise right heart catheterization. Non-invasive hemodynamic assessment on the use of liver ultrasound and MR elastography. 2) Myocarditis, Cardiac sarcoidosis, Inflammatory cardiomyopathy: clarifying the mechanisms, risk stratification, therapies. 3) Structural heart disease: hemodynamic assessment on the use of 4D-flow MRI.