Speaker illustration

Doctor Patrick Lacolley

Inserm U1116, Vandoeuvre-Les-Nancy (France)

Patrick Lacolley is specialized in cardiology and entered Inserm in 1987. He rapidly developed a particular interest for cellular and molecular determinants of arterial stiffness in hypertension, ageing, arterial thrombosis and heart failure. Since January 2005, he is director of the Inserm UMR_S 1116 which is devoted to the “Acute and chronic cardiovascular deficiency”, with expertise in molecular and cell biology and experimental animal models. The major findings concern (1) vascular smooth muscle cells as major determinants of arterial stiffness; (2) integrin-mediated membrane mechanotransduction in vascular remodeling, (3) natural connexions between arterial wall and coagulation.

Molecular insights into vascular ageing

Event: Frontiers in CardioVascular Biomedicine 2022

Topic: Atherosclerosis, Cerebrovascular Diseases, Aneurysm, Restenosis

Session: Physiological and pathological cardiovascular ageing


Role of vascular smooth muscles cells in naked mole rats during ageing (Heterocephalus glaber)

Event: ESC Congress 2019

Topic: Prevention

Session: Aortic Disease: animal, genetic, bench


The ageing vasculature: what is the issue?

Event: ESC Congress 2019

Topic: Stem Cells, Cell Cycle, Cell Senescence, Cell Death

Session: The ageing cardiovascular system: anything that can slow down the process?


Smooth muscle cells and arterial stiffness: clinical aspects.

Event: EuroPrevent 2019

Topic: Basic Science

Session: Arterial stiffness: from bench to bedside


ESC 365 is supported by

logo Novo Nordisk
logo Bristol Myers Squibb