In 2002, Dr Horie promoted to the full professor at the Shiga University of Medical Science, Japan. His area of interest is the basic/clinical cardiac electrophysiology as well as the molecular/genetic basis of inherited arrhythmia such as the long QT syndrome, Brugada syndrome, ACM, CPVT and calmodulinopathy. Familiar with basic EP study using patch-clamp techniques, molecular genetics, genetic testings, and clinical cardiology. Currently working on ion channel structure/function and its malfunction in cardiovascular diseases, which have been pursued consistently for last four decades. In 2018 he stepped down from the full professorship and continues to work as a research professor at the same institute.