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Dr. Komuro was graduated from The University of Tokyo in 1982 and after clinical residency, he has started research on mechanisms of cardiac hypertrophy and heart failure. He has reported that angiotensin II type 1 receptor is involved in mechanical stress-induced cardiac hypertrophy and has recently reported novel mechanisms of heart failure such as ischemia, inflammation and aging. He has also studied cardiac development and has isolated cardiac specific homeobox protein Nkx2.5. He has published more than 800 papers on peer-review journals including Natute, Cell and Nature Medicine.
