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Professor Jaap van Buul

Amsterdam University Medical Centre, Amsterdam (Netherlands (The))

It is my long-lasting interest to understand the process of leukocyte transendothelial migration (TEM) and how the vessel wall manages to maintain its integrity during this event. TEM is crucial during several (patho) physiological conditions, such as inflammation, atherosclerosis, but also during homing of hematopoietic stem cells after chemo-/radiotherapy and for cancer cell metastasis. Jaap D. van Buul is a professor of Vascular Cell Biology by special appointment at the Swammerdam Institute for Life Sciences at the University of Amsterdam. He did his postdoc in the lab of Prof. Dr. Keith Burridge at the Department of Developmental and Cell Biology at the University of North Carolina in Chapel Hill, USA. This was a wonderful period and showed for the first time a functional role for the small GTPase RhoG. In 2009, he co-founded the Dutch Endothelial Biology Society (DEBS), now the Netherlands Vascular Biology Organization (NeVBO), giving a platform to young researchers.

Endothelial leukocyte interactions

Event: Frontiers in CardioVascular Biomedicine 2024

Topic: Vascular Tone, Permeability, Microcirculation

Session: Endothelial leukocyte interactions

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Endothelial permeability, leakage and disease

Event: Frontiers in CardioVascular Biomedicine 2022

Topic: Microcirculation, Angiogenesis, Arteriogenesis

Session: Endothelial permeability, leakage and disease

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