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Professor Michael Brunner

St. JosefsHospital, Freiburg (Germany)
Membership: FESC Member EHRA Member
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Biography
A graduate of the University of Vienna (Austria), he wrote his thesis on thrombolysis in acute myocardial infarction and trained in internal medicine, cardiology and intensive care at the university clinics in Freiburg, Germany. During his Post-Doc at the Brigham and Women´s Hospital (Harvard Medical School) he studied animal models of the Long-QT-Syndrome and gene transfer using (adeno-)viral vectors to ameliorate the phenotype. His research interest are translational, creating the first human transgenic rabbits models of the Long- and the Short-QT Syndrome, aimed at understanding arrhythmogenesis and triggering and influencing factors such as hormones. He obtained a PhD at the University of Maastricht, and a Master in Health Business Administration. Clinically his focus is interventional cardiology, electrophysiology and intensive care.
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Contributor content

Mechano-electrical feedback in transgenic rabbit models of long QT syndrome Type 2 and short QT syndrome Type 1
Journal
Mechano-electrical feedback in transgenic rabbit models of long QT syndrome Type 2 and short QT syndrome Type 1
19 January 2026
AAV9-mediated <em>KCNH2</em> suppression-replacement gene therapy in a transgenic rabbit model of type 1 short QT syndrome
Journal
AAV9-mediated <em>KCNH2</em> suppression-replacement gene therapy in a transgenic rabbit model of type 1 short QT syndrome
30 August 2025
Beneficial action potential duration–shortening effects, but deleterious negative inotropism of <em>I<sub>Ks</sub></em>-activator docosahexaenoyl glycine in long QT syndrome type 2
Journal
Beneficial action potential duration–shortening effects, but deleterious negative inotropism of <em>I<sub>Ks</sub></em>-activator docosahexaenoyl glycine in long QT syndrome type 2
5 August 2025
<em>KCNQ1</em> suppression-replacement gene therapy in transgenic rabbits with type 1 long QT syndrome
Journal
<em>KCNQ1</em> suppression-replacement gene therapy in transgenic rabbits with type 1 long QT syndrome
8 August 2024
Beneficial normalization of cardiac repolarization by carnitine in transgenic short QT syndrome type 1 rabbit models
Journal
Beneficial normalization of cardiac repolarization by carnitine in transgenic short QT syndrome type 1 rabbit models
17 July 2024
Animals in cardiovascular research: important role of rabbit models in cardiac electrophysiology
Journal
Animals in cardiovascular research: important role of rabbit models in cardiac electrophysiology
15 May 2020

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