Profile picture

Professor Michael Holinstat

University of Michigan, Ann Arbor (United States of America)
Membership: ESC Professional Member
Follow
Biography
Dr. Michael Holinstat began his career as an assistant professor at Thomas Jefferson University in Philadelphia in 2009. In 2015, Dr. Holinstat moved his research lab to the University of Michigan where he is now a Professor in the department of Pharmacology and is a fellow of the American Heart Association. Dr. Holinstat’s research interests focus on understanding platelet signaling and function and how it relates to regulation of hemostasis and thrombosis with an emphasis on discovery of novel oxylipin and lipoxygenase targets in the platelet for the development of new therapeutic drugs for the treatment of cardiovascular diseases. Dr. Holinstat has received several national awards including the Kenneth M. Brinkhous Young Investigator Prize in Thrombosis from American Heart Association and the Young investigator Award in Structure-Function from the Eicosanoid Research Foundation. On a personal note, Dr. Holinstat is an avid trophy fisherman.
Logo ESC

Contributor content

CS585, a novel prostacyclin receptor agonist, demonstrates sustained efficacy in vivo in the prevention of thrombosis
Presentation
CS585, a novel prostacyclin receptor agonist, demonstrates sustained efficacy in vivo in the prevention of thrombosis
HDAC inhibitor CS014 inhibits platelet activity, small and large vessel thrombosis while maintaining haemostasis in a dose-dependent manner
Presentation
HDAC inhibitor CS014 inhibits platelet activity, small and large vessel thrombosis while maintaining haemostasis in a dose-dependent manner
CS014 is a novel HDAC inhibitor regulating the platelet activity, fibrinolysis and clot stability for prevention of thrombosis without increased risk of bleeding
Presentation
CS014 is a novel HDAC inhibitor regulating the platelet activity, fibrinolysis and clot stability for prevention of thrombosis without increased risk of bleeding

ESC 365 is supported by