Learning objectives:

After watching this webinar, participants will understand: 

• potential mechanisms underlying the cardiotoxicity of acute hyperglycemia;
• Its role in arrhythmogenesis; and
• putative treatment for reducing pro-arrhythmicity.

Needs assessment and expected educational outcome/

To determine how to address the cardiotoxicity of acute hyperglycemia in a significant number of acute coronary syndrome patients. Should we aggressively treat the hyperglycemia to reduce pro-arrhythmicity or should we target the pathways involved in glucose-induced arrhythmicity, given the significant risks associated with hyperglycemia? Those risks involve electrical disturbances in myocardial repolarisation, which become particularly acute when coupled with ischaemic events where dysregulation of intracellular calcium further exacerbates repolarisation dysfunction. Furthermore, cardioprotective interventions often fail in hyperglycemic patients and animal models.

Main topic

• pathophysiological and mechanisms 

Session information

This webinar is designed for Cardiologists, EP specialists, interventional cardiologists, metabolic medicine, mechanistic research scientists wishing to update their scientific knowledge on the topic.

During the webinar, you will be encouraged to send your questions by chat and interact with our key opinion leaders who will provide live feedback.