In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.

The free consultation period for this content is over.

It is now only available year-round to HFA Silver & Gold Members, Fellows of the ESC and Young combined Members

The presence of pulmonary hypertension and previous hospitalizations for heart failure are independent predictors of mortality or rehospitalisation in patients with advanced heart failure.

Session Poster session 1 Saturday 08:30 -17:30

Speaker Evelyn Santiago Vacas

Event : Heart Failure 2015

  • Topic : heart failure
  • Sub-topic : Chronic Heart Failure
  • Session type : Poster Session

Authors : E Santiago (Barcelona,ES), M A Castel Lavilla (Barcelona,ES), M Farrero (Barcelona,ES), M Cardona (Barcelona,ES), J Casal (Barcelona,ES), F Perez-Villa (Barcelona,ES)

E Santiago1 , M A Castel Lavilla1 , M Farrero1 , M Cardona1 , J Casal1 , F Perez-Villa1 , 1Hospital Clinico Universidad de Barcelona - Barcelona - Spain ,

European Journal of Heart Failure Abstracts Supplement ( 2015 ) 17 ( Supplement 1 ), 52

Objectives: The waiting time for heart transplantation (HTx) has steadily increased in Spain. This increases the risk for worsening heart failure (HF) and death in patients with advanced HF. Our aims were to assess characteristics of patients referred for evaluation to a HTx unit and identify predictors of mortality or hospitalization for HF.

Methods: Retrospective analysis of consecutive patients referred for evaluation to an outpatient clinic between 2011 and 2014. Endpoints evaluated were a) A combined end point of all cause mortality or hospitalization for HF and b) All cause mortality free of urgent HTx. Cox regression analysis and survival Kaplan-Meier curves were performed to identify predictors of risk.

Results: 125 patients were included, age 56.4 ± 9.8 y, 78% males, 41% ischemic CMP. Mean LVEF was 23.8 ± 6%, 56 (45%) had pulmonary hypertension (PH) and 63 (50%) reduced right ventricular (RV) function. After a median follow-up of 14 ± 10 m, 26 pats underwent HTx and 34 died or had hospitalization for HF. Total survival free of hospitalization or HTx was 72.8%. Cox regression analysis identified the presence of hospitalizations for HF in the previous 12 months (HR 1.8; 95% IC: 1.3-2.5; p < 0.001) and PH with and without RV dysfunction (HR 6.6, 95% IC: 1.2-37.5; p = 0.032 and HR 4.1, 95% IC: 1.4-12.5; p = 0.01) as independent predictors for death or rehospitalisation and the presence of hospitalization for HF as the only predictor for all cause mortality free of urgent HTx (HR 7.7, 95% IC:1.7-35.2;p = 0.008).

Conclusions: In patients with advanced HF, the presence of PH determined by echocardiography with or without RV dysfunction is predictor of death or rehospitalisation. Hospitalization for HF in the previous 12 months was an independent predictor of all cause mortality and HF.

Members get more

Join now
  • 1ESC Professional Members – access all resources from general ESC events 
  • 2ESC Association Members (Ivory, Silver, Gold) – access your Association’s resources
  • 3Under 40 or in training - with a Combined Membership, access all resources
Join now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim and Lilly Alliance, Bristol-Myers Squibb and Pfizer Alliance, Novartis Pharma AG and Vifor Pharma in the form of educational grants. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are