Lack of the extracellular matrix proteoglycan lumican in mice exacerbates left ventricular dilatation and contractile dysfunction upon pressure overload
Institute for Experimental Medical Research (IEMR), Ulleval University hospital, Oslo (Norway)
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Mitochondrial translocation of DUSP5 and PHLPP-1, protein phosphatases targeting ERK and Akt, cancels cell-protective signals of mitochondrial protective kinases under oxidative stress.
Dipeptidyl peptidase-4 inhibitor markedly enhances the cardioprotective efficacy of Sodium-glucose cotransporter-2 inhibitor in pre-diabetic rats with cardiac ischemia-reperfusion injury