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The tyrosine kinase inhibitor nilotinib inhibits discoidin domain receptor 2 in human aortic valves, increases aortic valve thickness and induces valvular interstitial cell calcification

Session: Late Breaking Basic and Translational Science - Atherosclerosis and Aortic Stenosis

Topic: Cardio-Oncology

Speaker: Professor M. Back (Stockholm, SE)

Event: ESC CONGRESS 2019


About the speaker

Professor Magnus Back

Karolinska University Hospital, Stockholm (Sweden)

9 presentations

4 more presentations in this session

Heat Shock Protein 25 Immunotherapy Post-Menopause is Superior to Estradiol in Targeting Atherogenesis, Plasma Cholesterol and PCSK9 Levels

3 September 2019 08:30 - 08:44

Speaker: Professor E. O'Brien (Calgary, CA)


A novel CT-based radiotranscriptomic signature of perivascular fat improves cardiac risk prediction in the SCOT-HEART and CRISP-CT studies

3 September 2019 08:44 - 08:58

Speaker: Professor C. Antoniades (Oxford, GB)


Clonal hematopoiesis of indeterminate potential (CHIP) in patients with degenerative aortic valve stenosis: incidence, clinical correlates, and prognostic significance following TAVI

3 September 2019 08:58 - 09:12

Speaker: Doctor S. Mas-Peiro (Frankfurt am Main, DE)


Dipeptidyl Peptidase-4 Inhibition to Prevent Calcific Aortic Valve Disease: Proof of Concept Study (DIP CAVD_POC)

3 September 2019 09:26 - 09:40

Speaker: Doctor J. Song (Seoul, KR)