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Doctor Marius Vantler

Cologne University Hospital - Heart Center, Cologne (Germany)

Importance of smooth muscle p110alpha/AKT/FOXO1 signaling for the development of abdominal aortic aneurysm

Event: ESC Congress 2023

Topic: Pathophysiology and Mechanisms

Session: A better understanding of mechanisms decisive for aortic and peripheral disease development

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Lack of PI 3-kinase isoform p110alpha impairs SMC differentiation and proliferation and promotes aortic aneurysm formation

Event: ESC Congress 2022

Topic: Atherosclerosis, Cerebrovascular Diseases, Aneurysm, Restenosis

Session: Clinical and basic science insights in vascular disease

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PI 3-kinase isoform PI3Kalpha controls smooth muscle cell functionality and protects against aortic aneurysm formation

Event: ESC Congress 2021 - The Digital Experience

Topic: Atherosclerosis, Cerebrovascular Diseases, Aneurysm, Restenosis

Session: Basic science e-posters

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Lack of PI 3-kinase isoform p110alpha in smooth muscle cells impairs aortic wall homoeostasis and thus promotes aortic aneurysm formation

Event: ESC Congress 2020

Topic: Pathophysiology and Mechanisms

Session: Diseases of the Aorta ePosters

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Deficiency of PI 3-kinase isoform p110alpha in smooth muscle cells impairs vascular integrity and promotes aortic aneurysm formation

Event: ESC Congress 2019

Topic: Atherosclerosis, Cerebrovascular Diseases, Aneurysm, Restenosis

Session: Vascular signalling

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SGC-stimulation via BAY 41-2272 exerts antiatherogenic effects in LDLR- and ApoE-deficient mice

Event: ESC Congress 2018

Topic: Drugs, Drug Targets

Session: Inflammation : vascular disease

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