In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.


The free consultation period for this content is over.

It is now only available year-round to HFA Silver & Gold Members, Fellows of the ESC and Young combined Members

Analysis of ICD therapies in patients with hypertrophic cardiomyopathy

Session Poster Session 4

Speaker Lisa Lauren Buttigieg

Congress : Heart Failure 2019

  • Topic : arrhythmias and device therapy
  • Sub-topic : Hypertrophic Cardiomyopathy
  • Session type : Poster Session
  • FP Number : P2148

Authors : L L Buttigieg (Malta,MT), M Zammit Burg (Malta,MT), T Felice (Malta,MT)

Authors:
L L Buttigieg1 , M Zammit Burg1 , T Felice1 , 1MaterDei Hospital, MaterDei Hospital - Malta - Malta ,

Citation:

Background: Patients suffering from Hypertrophic cardiomyopathy (HCM) are at an increased risk of sudden cardiac death (SCD). In Malta, there are approximately 150 patients with HCM being followed-up at the Inherited Cardiomyopathy Clinic of which 19 have had an Implantable Cardioverter Defibrillator (ICD) implanted. 

Purpose: To retrospectively analyse the risk of SCD and ICD therapies delivered in patients with HCM at our Hospital, Malta. 

Method: Data Collection was done using IT systems used in the Department of Cardiology (CVIS). The HCM Risk-SCD calculator was used appropriately to calculate risk of SCD at 5 years.

Results: Locally, 19 patients with HCM have had an ICD inserted. 69% were males and 31%  were females. The mean  age at device implantation was 50 years. ICDs were inserted in 2 patients <16years of age, in 1 patient with Fabry‚Äôs disease and in 3 patients for secondary prevention. For the other 13 patients, the HCM Risk SCD calculator was used to calculate risk of SCD at 5 years. 5 patients had >6% risk of SCD at 5 years meaning that ICD insertion should be considered whereas 8 patients had 4-6% risk of SCD at 5 years meaning that ICD insertion may be considered. Cardiac MRI was used in most borderline cases to decide regarding ICD insertion. 15.7% (n=3) had appropriate therapies for VT; n=2 had SCD risk>6% and n=1 had SCD risk 4-6% (SCD risk 5.92%) at 5 years. One patient received anti-tachypacing (ATP) and shock therapies whereas the other two patients received only ATPs. 15.7% (n=3) had inappropriate therapies for AF. 15.7% (n=3) had complications related to device insertion including upper limb thrombosis, upper limb swelling and lead dislodgement.

Conclusion: ICD therapies are effective in terminating ventricular arrhythmias leading to SCD in patients with HCM. Identifying patients at risk of SCD is still an ongoing challenge. 15.7% have received appropriate therapies for VT.



Based on your interests

Members get more

Join now
  • 1ESC Professional Members – access all resources from ESC Congress and ESC Asia with APSC & AFC
  • 2ESC Association Members (Ivory, Silver, Gold) – access your Association’s congress resources
  • 3Under 40 or in training - with a Combined Membership, access resources from all congresses
Join now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim and Lilly Alliance, Bristol-Myers Squibb and Pfizer Alliance, Novartis Pharma AG and Vifor Pharma in the form of educational grants. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are