In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.


This content is currently on FREE ACCESS, enjoy another 60 days of free consultation

 

Influence of hypertension on QT dispersion and systolic left ventricular function in patients with angina pectoris

Session Poster Session 3

Speaker Associate Professor Viktor Stoickov

Congress : Heart Failure 2019

  • Topic : hypertension
  • Sub-topic : Hypertension - Other
  • Session type : Poster Session
  • FP Number : P1833

Authors : V Stoickov (Nis,RS), M Deljanin Ilic (Nis,RS), M Stoickov (Niska Banja,RS), S Saric (Niska Banja,RS), D Marinkovic (Niska Banja,RS), I Tasic (Nis,RS), D Simonovic (Niska Banja,RS), I Stoickov (Nis,RS)

15 views

Authors:
V Stoickov1 , M Deljanin Ilic1 , M Stoickov2 , S Saric2 , D Marinkovic2 , I Tasic1 , D Simonovic2 , I Stoickov3 , 1University of Nis, Medical Faculty, Institute of Cardiology Niska Banja - Nis - Serbia , 2Institute of Cardiology - Niska Banja - Serbia , 3University of Nis, Medical Faculty - Nis - Serbia ,

Citation:

Introduction: QT dispersion (QTd) is a measure of inhomogeneous repolarization of myocardium and is used as an indicator of arrhythmogenicity. According to the values of QTd can identify coronary patients who are at high risk of cardiac death and sudden cardiac death.

Purpose: The aim of this study was to investigate the influence of hypertension on QT dispersion and systolic left ventricular function in patients with angina pectoris.

Methods: The study included 161 patients with angina pectoris (average age 56.8 years), of which 109 were with hypertension, and 52 were without arterial hypertension. There were no significant differences in age and gender between the two groups of patients. In all subjects echocardiographic examination were performed and from standard ECG corrected QT dispersion (QTdc) was calculated.

Results: Patients with angina pectoris and hypertension had significantly higher values of QTdc (58.7 ± 19.6 vs 44.9 ± 17.8 ms; p <0.001) compared to those without arterial hypertension. Also, patients with angina pectoris and hypertension had significantly lower values of left ventricular ejection fraction (58.6 ± 11.5 vs 63.2 ± 12.2%; p <0.025) and significantly higher values of the thickness of the interventricular septum (12.8 ± 1.9 vs 10.7 ± 1.6 mm; p <0.001), left ventricle posterior wall thickness (11.4 ± 1.6 vs 9.3 ± 1.4 mm; p <0.001), left ventricular end-systolic diameter  (38.9 ± 6.4 vs 36.1 ± 7.1 mm; p <0.02) and left atrium diameter (41.3 ± 4.7 vs 37.8 ± 5.3 mm; p <0.005) compared to those without hypertension. Patients with angina pectoris and arterial hypertension had  higher values of the left ventricular end-diastolic diameter (54.5 ± 5.5 vs 53.8 ± 6.9 mm; p-NS) compared to those without hypertension, but the differences were not statistically significant.

Conclusion: The study demonstrated that patients with angina pectoris and hypertension had significantly higher values of corrected QT dispersion and significantly reduced systolic left ventricular function compared to those without hypertension.



Based on your interests

Three reasons why you should become a member

Become a member now
  • 1Access your congress resources all year-round on the New ESC 365
  • 2Get a discount on your next congress registration
  • 3Continue your professional development with free access to educational tools
Become a member now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim, Bristol-Myers Squibb and Pfizer Alliance, and Novartis Pharma AG. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are