Purpose: To evaluate ECG parameter and echocardiographic(echo) dyssynchrony correlation with left ventricular(LV) dysfunction in pts with permanent pacemaker implantation(PPM)
Method: We evaluated 151 pts who had received PPM and were dependent on RV
pacing. The survey included clinical basic data, ECG parameters (pacing axis, QRS duration, QTc interval) and echo studies (LV ejection fraction[EF], LV end systolic dimension[ESD], septal flash, inter-ventricular mechanical delay[IVD], and septal-to-posterior wall motion delay [SPWMD]). Dyssynchrony was assessed by speckle-tracking strain using off-line software.
Results: Pts mean age was 75±13 years old and pacing duration was 79±61 months. Most (94%) RV lead located over apex. Mean LVEF was 61±12%. 11%(17/151) pts had EF below 40%. For ECG parameters, longer QRS and QTc are related with worse LVEF while more negative QRS axis with better EF. For echo parameters, longer SPWMD correlated with worse EF. The finding of septal flash, IVD and speckle tracking dyssynchrony had no significant relation. Duration of QRS also found to have high correlation to SPWMD(P<0.01).
Conclusion: Compared with more time consuming speckle tracking dyssnchrony, echo SPWMD and ECG parameter correlate better with LVEF in PPM pts.