Purpose: We sought to evaluate Se levels in Polish patients with myocardial infarction (MI), heart failure (HF) and healthy volunteers in relation to thyroid hormones levels.
The study group: We studied 143 persons: 54 consecutive patients with acute MI (group MI), 59 consecutive patients with decompensated HFrEF, (group HF) and 30 healthy volunteers (group C).
Exclusion criteria: thyroid dysfunction, severe systemic disease, treatment with amiodarone, steroids or propranolol.
Laboratory tests: TSH, fT3, fT4, Se levels were analysed.
Results: Se levels were lowered in both MI and HF patients in comparison to healthy controls (Table 1, Figure 1). Patients with MI and HF presented higher levels of TSH and lower levels of fT3 and fT3/fT4 ratio in comparison to controls (Table 1).
There was a moderate correlation between Se and: fT3 (r=0.390, p<0.0001) and fT3/fT4 ratio (r=0.4294, p<0.0001).
Conclusions: Se deficiency is frequent, unrecognized finding in both patients with acute MI and chronic HF in comparison to healthy volunteers. Further studies are needed to investigate if Se deficiency may play a negative role in patients with MI, and HF.