In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.

The free consultation period for this content is over.

It is now only available year-round to HFA Silver & Gold Members, Fellows of the ESC and Young combined Members

Inverse relationship between hemoglobin oxygen saturation measured by pulse oximetry at rest and exercise capacity in the patients with heart failure

Session Poster session 3

Speaker Naoki Aizawa

Event : Heart Failure 2017

  • Topic : preventive cardiology
  • Sub-topic : Exercise Testing
  • Session type : Poster Session

Authors : N Aizawa (Nishihara,JP), K Nagahama (Okinawa,JP), Y Toma (Nishihara,JP), H Ikemiyagi (Nishihara,JP), T Shinzato (Nishihara,JP), M Iwabuchi (Nishihara,JP), Y Ohya (Nishihara,JP)

Authors:
N Aizawa1 , K Nagahama2 , Y Toma1 , H Ikemiyagi1 , T Shinzato1 , M Iwabuchi1 , Y Ohya1 , 1University of the Ryukyus, Department of Cardiovascular Medicine, Nephrology and Neurology. - Nishihara - Japan , 2Okinawa Rehabilitation Center Hospital - Okinawa - Japan ,

Citation:
European Journal of Heart Failure ( 2017 ) 19 ( Suppl. S1 ), 493

Background: Exercise capacity is a key prognostic factor in the patients with heart failure (HF). Although peak oxygen consumption (peak VO2) measured by maximal symptom-limited cardiopulmonary exercise test (CPET) is the most objective method to determine exercise capacity, a simple tool to predict exercise capacity is required. Hemoglobin oxygen saturation measured by pulse oximetry (SpO2) is a simple and useful tool to evaluate oxygenation. However, the relationship between SpO2 at rest and exercise capacity measured by CPET is unclear.  
Purpose: To investigate the relationship between SpO2 at rest and exercise capacity measured by maximal symptom-limited CPET in the patients with HF.
Methods: We examined the association between SpO2 and exercise capacity among 46 patients with HF (age 54 ± 13, male 76%, cardiomyopathy 43%, valvular heart disease 35%, ischemic heart disease 17%) who underwent maximal symptom-limited CPET in our institute.
Results: Peak VO2/weight and peak respiratory exchange ratio were 16.2 ± 5.6 ml/min/kg and 1.2 ± 0.1, respectively. SpO2 at rest inversely correlated with peak VO2/weight (r = -0.43, P = 0.003). Compared with the patients who had preserved exercise capacity (peak VO2/weight = 11.0 ml/min/kg, n = 39), the patients who had low exercise capacity (peak VO2/weight < 11.0 ml/min/kg, n = 7) showed significantly higher SpO2 at rest (99.0 ± 0.8 vs 98.0 ± 1.6 %, P = 0.03). Multiple regression analysis revealed that higher SpO2 at rest (ß = -0.29, P = 0.006), age, BMI and lower hemoglobin, sodium are independent predictors of lower peak VO2/weight. 
Conclusion: In patients with HF, higher SpO2 at rest may detect lower exercise capacity.

Members get more

Join now
  • 1ESC Professional Members – access all resources from general ESC events 
  • 2ESC Association Members (Ivory, Silver, Gold) – access your Association’s resources
  • 3Under 40 or in training - with a Combined Membership, access all resources
Join now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim and Lilly Alliance, Bristol-Myers Squibb and Pfizer Alliance, Novartis Pharma AG and Vifor Pharma in the form of educational grants. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are