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Speech analysis to evaluate acute heart failure patient clinical status

Session HFA Discoveries - ePosters

Speaker Ronit Haviv

Event : HFA Discoveries 2020

  • Topic : e-cardiology/digital health. public health. health economics. research methodology
  • Sub-topic : Remote Patient Monitoring and Telehealth
  • Session type : ePosters

Authors : O Amir (Jerusalem,IL), WT Abraham (Ohio,US), ZS Azzam (Haifa,IL), SD Anker (Berlin,DE), SP Pinney (New York,US), D Burkhoff (New York,US), ID Shallom (Or Yehuda,IL), C Lotan (Jerusalem,IL), ER Edelman (Boston,US)

O Amir1 , WT Abraham2 , ZS Azzam3 , SD Anker4 , SP Pinney5 , D Burkhoff6 , ID Shallom7 , C Lotan1 , ER Edelman8 , 1Hadassah University Medical Center - Jerusalem - Israel , 2Ohio State University Hospital - Ohio - United States of America , 3Rambam Health Care Campus - Haifa - Israel , 4Charite - Campus Virchow-Klinikum (CVK) - Berlin - Germany , 5Mount Sinai Hospital - New York - United States of America , 6Cardiovascular Research Foundation - New York - United States of America , 7Cordio Medical - Or Yehuda - Israel , 8Institute for Medical Engineering and Science, Massachusetts Institute of Technology - Boston - United States of America ,

Remote Patient Monitoring and Telemedicine


Pulmonary congestion that accompanies heart failure (HF) can produce subtle changes in speech patterns, the measurement of which may be a valuable tool for assessing a HF patient clinical status.


We investigated how speech signal processing algorithms detect these changes in patients with acute HF (AHF) throughout their admission and evaluate the potential clinical utility of this approach.


We recruited 40 patients admitted with AHF mean age 75 ±12 (50% female) and mean LVEF 53 ±15. We studied the use of speech processing algorithms in digitally measured speech samples in these AHF patients at hospital admission ("wet") and discharge ("dry"). Patients were discharged after diuretic treatment and clinical improvement.

We analyzed speech patterns, expressed as numerical values denoted "speech measures" (SM), in a single arm, open label, non-interventional study.  Each patient read out loud and recorded 3-5 prescribed sentences while wet and dry. These recordings underwent processing using a range of algorithms to report five different SMs, denoted SM1, SM2, SM3, SM4 and SM5. Data were presented as SM at admission (SMa), SM at discharge (SMd), and Delta SMs (DSMs) defined as the relative change from admission to discharge, i.e. (SMd-SMa)/SMa.


Speech processing detected a substantial mean change in the 5 SMs between wet and dry states, (Figure 1, p<0.001).


Speech processing provided a clear signal difference between the congested wet state at admission and the compensated dry state at discharge, in these AHF patients. Such digital speech processing offers a readily available, non-invasive means of monitoring congestion and HF clinical status in HF patients that may be implemented in the hospital, in the clinic or in the outpatient setting.

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