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Effects of short-time physical training in heart failure patients after surgical revascularization

Session Poster Session 1

Speaker Dragan Marinkovic

Event : Heart Failure 2016

  • Topic : preventive cardiology
  • Sub-topic : Exercise Testing
  • Session type : Poster Session

Authors : D Marinkovic (Nis,RS), M Deljanin-Ilic (Nis,RS), B Ilic (Nis,RS), D Petrovic (Nis,RS), D Simonovic (Nis,RS), S Stojanovic (Nis,RS), S Ignjatovic (Nis,RS)

D Marinkovic1 , M Deljanin-Ilic2 , B Ilic1 , D Petrovic1 , D Simonovic1 , S Stojanovic1 , S Ignjatovic1 , 1Institute for Treatment and Rehabilitation Niska Banja - Nis - Serbia , 2University of Nis, Medical Faculty, Institute of Cardiology Niska Banja - Nis - Serbia ,

European Journal of Heart Failure Abstracts Supplement ( 2016 ) 18 ( Supplement 1 ), 115

Aim: To evaluate the effects of short-term physical training on physical exercise tolerance and level of markers of inflammation, neuro-humoral activation and endothelial function, in CHF patients after surgical revascularization. Methods: The study involved 43 patients (32 males); mean age 60.3 ± 5.7 years, mean EF 34.75 ± 3.34%, NYHA II and III, after surgical revascularization procedures. All patients were included in three-weeks rehabilitation program in the residential center, based on strictly controlled and individually prescribed physical training. Before and after rehabilitation, all patients were underwent exercise stress test, and from the veins blood samples, biochemical markers of inflammation, atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) an endothelin (ET) were determined. Results: At the end of the study the hs-CRP and fibrinogen level were showed a decreasing trend (ns). After cardiovascular rehabilitation a significant reduction in white blood cells count was recorded (p = 0.028). Erythrocyte sedimentation rate after rehabilitation was higher, but not significant. In all pts, the concentration of ANP and BNP was higher after 3 weeks compared to baseline values (p = 0.043; p = 0.015). In contrast, the value of endothelin after rehabilitation was lower than baseline value (p = 0.112), but not significant. At end of this study, significantly higher serum HDL-cholesterol in CHF patients was found (p=0,001). Exercise tolerance was improved, as well as quality of life assessed by Minnesota Living With Heart Failure Questionnaire. Conclusion: CHF patients after surgical revascularization residential short-term training decreased the level of inflammatory status and ET and transitory increase ANP and BNP. Those positive effects are associated in significant increases of exercise tolerance and improve of quality of life.

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