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Stress at work burden as new risk factor in patients with acute cerebro or cardiovascular events: preliminary findings from INEV@L, a prospective pilot study

Session Poster Session 2

Speaker Marianne Zeller

Congress : EuroPrevent 2019

  • Topic : preventive cardiology
  • Sub-topic : Stress, Psycho-Social and Cultural Aspects of Heart Disease
  • Session type : Poster Session
  • FP Number : P605

Authors : M Zeller (Dijon,FR), E Sales-Wuillemin (Dijon,FR), J Chappe (Dijon,FR), S Guinchard (Dijon,FR), H Ayari (Dijon,FR), M Maza (Dijon,FR), C Aboa-Eboule (Dijon,FR), D Truchot (Besançon,FR), L Lorgis (Dijon,FR), F Chague (Dijon,FR), M Giroud (Dijon,FR), Y Cottin (Dijon,FR), Y Bejot (Dijon,FR)

M Zeller1 , E Sales-Wuillemin2 , J Chappe2 , S Guinchard3 , H Ayari3 , M Maza4 , C Aboa-Eboule4 , D Truchot5 , L Lorgis4 , F Chague4 , M Giroud3 , Y Cottin4 , Y Bejot3 , 1Université de Bourgogne Franche Comté, PEC2, EA7460 - Dijon - France , 2Université de Bourgogne Franche Comté, PSY-DREPI Laboratory, EA 7458 - Dijon - France , 3University Hospital Center, Neurology Department - Dijon - France , 4University Hospital Center, Cardiology Department - Dijon - France , 5Université de Bourgogne Franche Comté, Psychology Department - Besançon - France ,


Introduction and aim: Although psychosocial factors (PSF) including work-related stress and low quality of life at work are emerging cardiovascular risk factors, PSF burden remains poorly investigated after acute cerebro or cardiovascular event (CVE).

Methods: INEV@L, an ongoing prospective multidisciplinary study, included 156 patients aged < 65 y, currently working and hospitalized for stroke or MI between 1st January 2016 and 31st august 2017. PSF were examined (perceived CV disease severity, anxiety/depression, perceived stress at work (PSW), quality of life at work (QLW) through validated questionnaires and semi-conducted interviews. Patients with higher (supramedian) perceived stress at work (PSW) were compared to lower (inframedian) PSW.
Results: The 156 patients included (121(78%) acute MI, 35(22%) stroke) had a median(IQR) age at 53(48-58) years, 18% were women, 56% smokers. They had high PSW (15(10-20)), but a low QLW (85(75-95)). Patients with high PSW had similar risk factors including age (p=0.450), women (0.542), hypertension (p=0.791), smoking (p=0.384), diabetes (p=0.193), obesity (p=0.995) than patients with lower PSW. Although high PSW patients showed a trend toward lower education level (p=0.067), marital status, and socioeconomic categories were similar for both groups.  Elevated perceived disease severity was more common (49 vs 29%, p=0.011) in stressed patients. Patients with high PSW are more anxious (78 vs 25%, p<0.001), and had twice more depressive symptoms (19 vs 9%, p=0.100). QLW was significantly lower in high PSW patients (81±16 vs 90±13, p<0.001). Moreover, QLW was strongly correlated with PSW (r=-0.433, p<0.001). Conclusion: These preliminary data from a prospective pilot study shows a high PSF burden in patients hospitalized for acute CVE. If confirmed at a larger scale, our data could identify new opportunities for secondary preventive strategies.

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