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Laughter therapy increases functional capacity in patients with coronary artery disease: a randomized clinical trial

Session Poster Session 1

Speaker Associate Professor Ricardo Stein

Congress : EuroPrevent 2019

  • Topic : preventive cardiology
  • Sub-topic : Cardiovascular Rehabilitation
  • Session type : Poster Session
  • FP Number : P299

Authors : R Stein (Porto Alegre,BR), A Donelli Da Silveira (Porto Alegre,BR), D Do Santos Macedo (Porto Alegre,BR), J Beust De Lima (Porto Alegre,BR), J Maia Delfino (Porto Alegre,BR), L Tolfo Franzoni (Porto Alegre,BR), M Aurelio Lumertz Saffi (Porto Alegre,BR), RM Nery (Porto Alegre,BR)


R Stein1 , A Donelli Da Silveira1 , D Do Santos Macedo1 , J Beust De Lima1 , J Maia Delfino1 , L Tolfo Franzoni1 , M Aurelio Lumertz Saffi2 , RM Nery2 , 1Federal University of Rio Grande do Sul - Porto Alegre - Brazil , 2Hospital de Clínicas de Porto Alegre - Porto Alegre - Brazil ,


Background: The impact of a laugher therapy cardiac rehabilitation (LTRehab) program for patients with coronary artery disease (CAD) has yet to be assessed. 

Purpose: To evaluate the potential effect of LTRehab (comedy sessions) on functional capacity in stable CAD patients

Methods: A single-blind randomized clinical trial (RCT) was conducted. The researchers who performed the tests were blinded to group allocation. Peak oxygen uptake (VO2peak) was measured by a maximal cardiopulmonary exercise testing (CPET). Patients allocated to LTRehab (n=12) watched two weekly sessions of a self-selected comedy and the control group (n=12) watched two weekly sessions of a neutral documentary (24 movies per group). ANCOVA was performed to estimate VO2peak main effect adjusted to baseline values.

Results: Twenty-four CAD individuals (70% male; 64±10 years) were included. After 12 weeks of intervention, VO2peak increased significantly in LTRehab group (10%) compared to control (19.4 ± 2.9 to 21.4 ± 3.4vs 23.2 ± 6.3 to 22.2 ± 7.1, pre and post intervention, respectively; P=0.005). All CPET reached maximal criteria (R>1.10). 

Conclusion: This is the first RCT to evaluate LTRehab in CAD patients. It was associated with an increase in VO2peak and may constitute an effective form of cardiac rehabilitation in this patient population.

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