Purpose: To evaluate the potential effect of LTRehab (comedy sessions) on functional capacity in stable CAD patients
Methods: A single-blind randomized clinical trial (RCT) was conducted. The researchers who performed the tests were blinded to group allocation. Peak oxygen uptake (VO2peak) was measured by a maximal cardiopulmonary exercise testing (CPET). Patients allocated to LTRehab (n=12) watched two weekly sessions of a self-selected comedy and the control group (n=12) watched two weekly sessions of a neutral documentary (24 movies per group). ANCOVA was performed to estimate VO2peak main effect adjusted to baseline values.
Results: Twenty-four CAD individuals (70% male; 64±10 years) were included. After 12 weeks of intervention, VO2peak increased significantly in LTRehab group (10%) compared to control (19.4 ± 2.9 to 21.4 ± 3.4vs 23.2 ± 6.3 to 22.2 ± 7.1 mL.kg-1.min-1, pre and post intervention, respectively; P=0.005). All CPET reached maximal criteria (R>1.10).
Conclusion: This is the first RCT to evaluate LTRehab in CAD patients. It was associated with an increase in VO2peak and may constitute an effective form of cardiac rehabilitation in this patient population.