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Coronary artery disease risk difference between liitle young and middle age group in india.

Session Poster Session 3

Speaker Naresh Sen

Event : ESC Preventive Cardiology (Formerly EuroPrevent) 2018

  • Topic : preventive cardiology
  • Sub-topic : Risk Factors and Prevention – Cardiovascular Risk Assessment
  • Session type : Poster Session

Authors : N Sen (BANGALORE,IN), SONAL Tanwar (Jaipur,IN), ASHOK Jain (Jaipur,IN), GEORGE Cherian (Bangalore,IN), S Jagdish (Jaipur,IN)

N Sen1 , SONAL Tanwar2 , ASHOK Jain3 , GEORGE Cherian4 , S Jagdish5 , 1NARAYANA HRUDAYALAYA INSTITUTE OF MEDICAL SCIENCE - BANGALORE - India , 2Rajasthan University of Health Sciences, Cardiology - Jaipur - India , 3Narayana Hrudayalaya, Cardiology - Jaipur - India , 4Narayana Hrudayalaya Institute of Medical Sciences, Cardiology - Bangalore - India , 5HG SMS Hospital, Cardiology - Jaipur - India ,

European Journal of Preventive Cardiology ( May 2018 ) 25 ( Supplement 1 ), 124

Background: Coronary artery disease  (CAD) is a major cause of morbidity and a leading contributor to mortality worldwide. Heart Disease will become a major cause of death and disability in new millennium. Angina (stable or unstable ) and Myocardial Infarction is a common presentation of Coronary Artery Disease .
Objectives: To compare the risk factors profile for coronary artery disease in little young (18 to35 years) and middle age( 36 to 55 years) subjects.
Methods: Total 5100 patients (2500  subjects 18 to 35 years of age and 50 subjects 36 to 55 years of age) with acute coronary syndrome or stable angina who were undergoing coronary angiogram were evaluated for the presence coronary artery disease risk factors e.g. hypertension, diabetes mellitus , dyslipidemia, smoking , obesity , homocysteine ,hs- CRP and stress factors.
Results: The mean age of the study population in little younger age group A was (26 ± 7.8) years and in middle age group B (46.0±8.4). The male to female ratio in group A was 4:1 and 3:1 in group B. Smokers were more in younger group (74.0% vs. 40.0%) (p = 0.051). Hypertension was less in the younger group (30.0% vs. 60.0%) (p = 0.036). Presence of diabetes was higher in the middle age group (38.0% vs. 7.0%) (p = 0.002). Higher incidence of family history of coronary heart disease was in the younger age group. The total cholesterol was higher in middle age group (194.5 ± 38.4) vs. (169.4 ± 30.2 mg/dl) (p = 0.054). 66 % of patients of middle age group and 34 % of younger group had stenosis in left anterior descending artery (p = 0.004). The involvement of left circumflex and right coronary artery in older age group were higher (56% and 66% respectively) than those in younger group (36% and 40% respectively) (p = 0.045 and p = 0.009).
Conclusion: Ischemic heart disease in younger adults < 35 years had different risk profile characteristics than older patients.

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