In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.

The free consultation period for this content is over.

It is now only available year-round to EAPC Ivory (& above) Members, Fellows of the ESC and Young combined Members

Carotid intima media thickness in patients with cardiac syndrome X and its association with impairment of coronary angiography indexes

Session Poster Session III - Friday 08:30 - 12:30

Speaker

Event : ESC Preventive Cardiology (Formerly EuroPrevent) 2015

  • Topic : preventive cardiology
  • Sub-topic : Risk Factors and Prevention
  • Session type : Poster Session

Authors : V Sucato (Palermo,IT), E Corrado (Palermo,IT), S Evola (Palermo,IT), A Sansone (Palermo,IT), G Novo (Palermo,IT), G Coppola (Palermo,IT), G Andolina (Palermo,IT), P Assennato (Palermo,IT), S Novo (Palermo,IT)

Authors:
V Sucato1 , E Corrado1 , S Evola1 , A Sansone1 , G Novo1 , G Coppola1 , G Andolina1 , P Assennato1 , S Novo1 , 1University Hospital Paolo Giaccone, Biomedical Department of Internal Medicine (DiBiMIS) - Palermo - Italy ,

Citation:

Purpose: The aim of this study was to evaluate in patients with cardiac syndrome X (CSX) the relationship between microvascular dysfunction and increase of carotid intima media thickness (C-IMT) using validated angiography indices

Methods: Our study was performed on a population 124 patients with CSX that underwent coronary angiography and carotid ultrasound. We divided the sample into two categories: patients with increase of C-IMT and those without increase. We calculated, on angiographic images, validate angiography indexes like TIMI Frame Count (TFC) and Myocardial Blush Grade (MBG) on three major coronary arteries.

Results: Our sample compared two groups: patients with increase of C-IMT (n-63) and patients without increase of C-IMT (n-61). Analysis trough angiography indexes showed that patients with increase C-IMT had a longest TFC of three major coronary arteries (TFC LAD 44, 7 +/- 12, 5; TFC RCA 26, 2 ± 6.9; TFC CX 27 ± 5,9), than control group, index of a coronary flow slowed with good statistical result on left anterior descending artery (p value 0.02), circumflex coronary artery (p-value 0.05). So, we found lower MBG on three coronary arteries (MBG LAD 2,5 ± 0,3; MBG RCA  2,3 ± 0,3; MBG CX 2,1 ±  0,32) in patients with increase of C-IMT than control group, with good statistical significance on left anterior descending artery (p value 0.02), circumflex coronary artery (p-value 0.04). 

Conclusion: Analysis of microcirculation trough angiography indexes in patients with CSX with increase of  C-IMT and without has led to asses that patients with increase of C-IMT population has a greater involvement of microcirculation than patients without.

Increase of C-IMT group

(n-63)

Control group

(n-61)

p-value

MBG LAD (n ± d.s)

2,5 ± 0,3

2,8 ± 0,6

0,02

MBG RCA (n ± d.s)

2,3 ± 0,3

2,2 ± 0,41

ns

MBG CX (n ± d.s)

2,1 ± 0,32

2,4 ± 0,47

0,04

TMBS (n ± d.s)

7 ± 1,22

7,4 ± 1,26

0,02

TFC LAD (n ± d.s)

48,1 ± 12,8

42,7 ± 11,9

0,02

TFC RCA (n ± d.s)

26,2 ± 6.9

25,8 ± 6,7

ns

TFC CX (n ± d.s)

27 ± 5,9

23 ± 5,2

0,05

TTFC (n ± d.s)

107,3 ± 14,5

102 ± 11,2

0,02

Members get more

Join now
  • 1ESC Professional Members – access all resources from general ESC events 
  • 2ESC Association Members (Ivory, Silver, Gold) – access your Association’s resources
  • 3Under 40 or in training - with a Combined Membership, access all resources
Join now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim and Lilly Alliance, Bristol-Myers Squibb and Pfizer Alliance, Novartis Pharma AG and Vifor Pharma in the form of educational grants. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are