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Gender differences in the severity and in-hospital treatment of patients with an acute myocardial infarction (AMI)

Session Poster Session III - Friday 08:30 - 12:30

Speaker Associate Professor Sokol Myftiu

Event : ESC Preventive Cardiology (Formerly EuroPrevent) 2015

  • Topic : preventive cardiology
  • Sub-topic : Risk Factors and Prevention
  • Session type : Poster Session

Authors : S Myftiu (Tirana,AL), I Sharka (Tirana,AL), XH Belshi (Tirana,AL), E Saja (Tirana,AL), E Sulo (Bergen,NO), A Shkoza (Tirana,AL), G Sulo (Bergen,NO)

S Myftiu1 , I Sharka1 , XH Belshi1 , E Saja1 , E Sulo2 , A Shkoza3 , G Sulo2 , 1"University Hospital Center ""Mother Theresa""", Department of Cardiology - Tirana - Albania , 2Department of Global Public Health and Primary Care - Bergen - Norway , 3University Hospital Center Mother Theresa, Department of Biomedical Sciences - Tirana - Albania ,


Purpose - Gender differences in the characteristics of patients with an AMI can influence the treatment and explain (partially or totally) the observed gender differences in survival. We aimed at exproring gender differences in AMI severity and treatment  among patients hospitalized at the University Hospital Center.
Methods - A total of 266 consecutive patients [mean age (SD), 64.9 (12.2) years; 22.6% women] were included in the study. Information on socio demographic variables, coronary risk factors, treatment and severity of the disease (defined as congestive heart failure and major arrhythmias) were obtained from the patients’ journal by two cardiology residents.
Logistic regression models were used to explore gender differences in severity and in-hospital treatment among AMI patients. Models were adjusted for age. Results are expressed as odds ratios (OR) and 95% CI for women versus men.
Results -Women were more likely to be obese (OR=2.46; 95% CI, 1.10-5.51) and have diabetes (OR=2.14; 95% CI, 1.15-3.99) but smoked less than men (OR=0.08; 95% CI, 0.04-0.17) while no gender differences were observed with regard to hypertension and dyslipidemia.
Clinical manifestation of AMI (defined as presence of major arrhythmias and/or congestive heart failure) was more severe among women (OR=2.16; 95% CI, 1.16-4.01).
Women were also less likely to receive PCI (OR=0.45; 95%CI, 0.20-0.98) and aspirin (OR=0.30; 95%CI, 0.10-0.90) compared to men while no gender differences were observed with regard to receiving statins, beta-blockers and ACE-inhibitors/ARBs.
Conclusions - Further studies including information on pre-hospitalization conditions are required to further explore reasons for such gender differences in some risk factors and treatment of the acute phase of MI.

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