In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.


The free consultation period for this content is over.

It is now only available year-round to EAPC Ivory (& above) Members, Fellows of the ESC and Young combined Members

Inverse association between central obesity and arterial stiffness in Korean subjects with metabolic syndrome: a cross-sectional cohort study

Session Poster Session III - Friday 08:30 - 12:30

Speaker Assistant Professor Ki-Bum Won

Congress : EuroPrevent 2015

  • Topic : preventive cardiology
  • Sub-topic : Obesity
  • Session type : Poster Session
  • FP Number : P529

Authors : K-B Won (Daegu,KR), H-J Chang (Seoul,KR), I-J Cho (Seoul,KR), C-Y Shim (Seoul,KR), G-R Hong (Seoul,KR), N Chung (Seoul,KR)

15 views

Authors:
K-B Won1 , H-J Chang2 , I-J Cho2 , C-Y Shim2 , G-R Hong2 , N Chung2 , 1Keimyung University Hospital Dongsan Medical Center, Cardiology - Daegu - Korea, Republic of , 2Yonsei Cardiovascular Hospital, Yonsei University College of Medicine, Cardiology Division - Seoul - Korea, Republic of ,

Citation:

Introduction: Metabolic syndrome (MetS) is associated with increased risks of diabetes and atherosclerotic cardiovascular disease. Whether central obesity (CeO) is a prerequisite for the diagnosis of MetS in the International Diabetes Federation (IDF) definition is a substantial issue because it may influence the clinical value of MetS for predicting subclinical atherosclerosis.

Methods: We investigated the relation between MetS, as defined by the National Cholesterol Education Program–Adult Treatment Panel III criteria, and arterial stiffness measured using brachial-ankle pulse wave velocity (baPWV) according to CeO status in 2,560 healthy Korean subjects who participated in a community-based cohort study.

Results: The prevalence of MetS was 40%; 85% of MetS subjects had CeO. The prevalence of diabetes was higher in MetS subjects than in non-MetS subjects (30 vs. 8%, p<0.001). The number of MetS components (MetSN) was correlated with baPWV (r=0.311, p<0.001). In a subgroup analysis of MetS subjects, the prevalence of diabetes was not significantly different in MetS subjects with and without CeO. MetS subjects without CeO had higher baPWV than those with CeO (1654±315 vs. 1578±270 cm/s, p=0.002). Multiple regression models revealed that CeO was inversely associated with baPWV in MetS subjects.

Conclusion: Despite the significant correlation between MetSN and arterial stiffness, there appeared to be an inverse association between CeO and arterial stiffness in MetS subjects. In contrast to the IDF definition, CeO might not be crucial for the diagnosis of MetS in healthy Koreans having multiple metabolic risk factors with respect to subclinical atherosclerosis reflected in arterial stiffness.



Based on your interests

Three reasons why you should become a member

Become a member now
  • 1Access your congress resources all year-round on the New ESC 365
  • 2Get a discount on your next congress registration
  • 3Continue your professional development with free access to educational tools
Become a member now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim, Bristol-Myers Squibb and Pfizer Alliance, and Novartis Pharma AG. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are