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1Altay State Medical University - Barnaul - Russian Federation
2Railway Clinical Hospital - Barnaul - Russian Federation
Objective: explore prognosis masked hypertension in men with occupational stress without cardiovascular disease (CVD).
Materials and Methods: A total of 99 drivers and their assistants. Conducted identification of hypertension and masked hypertension. The survey was conducted at intervals of five years. The masked hypertension determined from the stress test "Mathematical expense." The test was positive for growth in systolic blood pressure (sBP) > 7% and/or increment of heart rate > 10%. Identified 2 groups: the first group - a man with a masked hypertension (n = 40, age 42,8 ± 9,8 years); 2nd group - men with normal blood pressure (BP) (n = 59, age 42,3 ± 8,4 years).
Results: In both groups, according to stress test a marked rise in BP and heart rate. The highest values ??of BP and heart rate were the men of the 1st group. Important growth indicators, since it was he who reflects stress reactivity examined. In men, the first group compared with the second stress test on the increase sBP was 2.2 times higher (p < 0,001) increase in heart rate 2.3 times higher (p < 0,001). Increase in diastolic BP (dBP) in the 1st group was higher by 24% (p < 0,05). Risk factors in the 1st group compared with the second: a history of CVD met 2,2 times more often (?2 = 9,22, p < 0,002) (58% in the 1st group and 27% in the 2nd group); smoking status 1,8 times more often (frequency 77,5%) (?2 = 11,9, p < 0,0005); abdominal obesity is 2,3 times more often (?2 = 6,69, p < 0,001) (42.4% in the 1st group and 18.6% in the 2nd group); Hypercholesterolemia was defined more by 2,3 times (?2 = 10,07, p < 0,001) and was 55%.
After 5 years, have been re-examination of the two groups of men with a diagnosis of hypertension and masked hypertension. For 5 years, hypertension was detected in 25% (10 of 40) - all of these men belonged to the group of individuals with masked hypertension. After 5 years, the stress test was positive in the same men as in the first survey, which indicates the constancy of stress reactivity hemodynamics.
Conclusions: The incidence of hypertension in individuals with masked hypertension within 5 years is 25%. Application of a stress test "Mathematical account" allows to diagnose in the early stages of hemodynamic changes and start timely prevention. Stress-reactivity is stable hemodynamic changes in the cardiovascular system and in the presence of additional risk factors such as smoking, hypercholesterolemia, and abdominal obesity, realized within five years hypertension.
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