In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.

The free consultation period for this content is over.

It is now only available year-round to ACNAP Silver Members, Fellows of the ESC and Young combined Members

Effect of adding chocolate with high cocoa content to the usual diet of postmenopausal women on blood pressure and arterial stiffness markers. Randomized clinical trial

Session Moderated poster session - Public health and cardiac rehabilitation

Speaker Assistant Professor Jose Ignacio Recio-Rodriguez

Congress : EuroHeartCare 2019

  • Topic : hypertension
  • Sub-topic : Hypertension - Treatment
  • Session type : Moderated Posters
  • FP Number : 25

Authors : J I Recio-Rodriguez (Burgos,ES), I Garcia-Yu (Burgos,ES), B Sanchez-Salgado (Salamanca,ES), L Garcia-Ortiz (Salamanca,ES), C Agudo-Conde (Salamanca,ES), M Gomez-Marcos (Salamanca,ES), O Tamayo-Morales (Salamanca,ES), J Gonzalez-Sanchez (Salamanca,ES), E Rodriguez-Sanchez (Salamanca,ES), C Lugones-Sanchez (Salamanca,ES), J A Maderuelo-Fernandez (Salamanca,ES)

J I Recio-Rodriguez1 , I Garcia-Yu2 , B Sanchez-Salgado3 , L Garcia-Ortiz3 , C Agudo-Conde3 , M Gomez-Marcos3 , O Tamayo-Morales3 , J Gonzalez-Sanchez3 , E Rodriguez-Sanchez3 , C Lugones-Sanchez3 , J A Maderuelo-Fernandez3 , 1Universidad de Burgos, Facultad de Ciencias de la Salud - Burgos - Spain , 2Gerencia de Atencion Primaria - Burgos - Spain , 3Primary Health Care Research Unit, La Alamedilla Health Center, IBSAL - Salamanca - Spain ,

On behalf: La Alamedilla Primary Care Research Unit



The intake of polyphenols has shown certain effects on cardiovascular health, especially in populations with an increased cardiovascular risk.


This work evaluates the effect of adding 10g. of chocolate with 99% cocoa content to the usual diet, on blood pressure and arterial stiffness markers in postmenopausal women.


Randomized clinical trial with two parallel groups that included 61 women (26 control and 35 intervention) between 50-64 years in postmenopausal period contrasted by amenorrhea of 12 months. Personal history of cardiovascular disease and presence of high blood pressure, diabetes mellitus or dyslipidemia were exclusion criteria. Blood pressure was measured with an oscillometric device and the brachial-ankle pulse wave velocity (baPWV) and the cardio-ankle vascular index (CAVI). The intervention group received instructions for the daily intake of 10 g. of chocolate with 99% of cocoa added to your usual diet, for 3 months. The nutritional contribution of this product is 59 kcal and 65.4 mg of polyphenols per day. There was no intervention in the control group. All the variables were measured in the baseline assessment and at 3 months post-randomization. The recruitment began in June 2018.


The mean age was 58.3±3.6 years. The values of systolic blood pressure-SBP 109.0±13.9, baPWV 7.95±1.00 and CAVI 4.57±0.52 (p>0.05 in all, with the exception of CAVI (Intervention 4.39±0.47, control 4.79±0.50, p=0.002). No differences were found between groups in the evolution of any of the variables studied after adjustment for the baseline value (SBP p=0.290, baPWV p=0.782, CAVI p=0.502). The control group decreased SBP -2.9 (-0.4 to 6.2), p>0.05, and baPWV -0.26 (-0.04 to -0.49), p<0.05. The intervention group decreased SBP -5.0 (-1.1 to -8.9), p=0.012, and the baPWV -0.22 (-0.04 to -0.40), p=0.016. Both groups slightly increase their CAVI values without reaching statistical significance.

CONCLUSIONS Add 10 g. of chocolate with a high proportion of cocoa to the usual diet of postmenopausal women for 3 months, does not provide additional benefits against non-supplementation, in the blood pressure figures, baPWV and CAVI. Although the reduction is stronger in the case of the experimental group for the SBP and the baPWV. More studies, with more women and more follow-up, are necessary to evaluate the effects of cocoa polyphenols on the cardiovascular health of postmenopausal women.

The free consultation period for this content is over.

It is now only available year-round to ACNAP Silver Members, Fellows of the ESC and Young combined Members

Based on your interests

Members get more

Join now
  • 1ESC Professional Members – access all resources from ESC Congress and ESC Asia with APSC & AFC
  • 2ESC Association Members (Ivory, Silver, Gold) – access your Association’s congress resources
  • 3Under 40 or in training - with a Combined Membership, access resources from all congresses
Join now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim and Lilly Alliance, Bristol-Myers Squibb and Pfizer Alliance, Novartis Pharma AG and Vifor Pharma in the form of educational grants. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are