Purpose : The aim of this study was to assess the effect of balloon mitral valvuloplasty (BMV)on global ventricular functions using 2D strain to understand the reversibility of reduced LV mechanical performance in patients with MS
Methods: Conventional echocardiography and longitudinal 2D strain analysis were performed in15 patients (33 +/-9 years) with severe MS (0,9 ± 0,2 cm²) and 15 healthy controls (37 +/-6 years). The mitral valve area was mesured by planimetry and pressure half time methods.
In MS patients, mesurements were repeted within 48 hours after BMV.
Results: patients with MS had significantly lower LV end-diastolic volume and GLS compared with control group(p:0,001).48 hours after BMV ,LV strain significantly improved (-19,2%vs -17,05 % p<0,05).
On multivariate analysis, left atrial volume, mean transmitral gradient, and LV end-diastolic volume were independently correlated with baseline GLS, whereas increment in LV end-diastolic volume was the only determinant of increased GLS after BMV.
Conclusion: Abnormalities of LV deformation in MS patients are correlated with the hemodynamic severity of the stenosis.BMV results in marked improvement in LV GLS which seems be related to the improvement of LV filling.