Purpose: To explore echocardiographic Task Force Criteria of 2010 parameters and their relation to ventricular arrhythmias in female AC patients.
Methods: We examined female AC patients by echocardiography. Right ventricular (RV) fractional area change (RV FAC) was measured, along with RV basal diameter (RVD) and RV outflow tract diameter (RVOT) which were reported as absolute and indexed values. We also assessed left ventricular ejection fraction (LVEF). Ventricular arrhythmia was defined as sustained ventricular tachycardia or fibrillation, aborted cardiac arrest or appropriate therapy from an implantable cardioverter-defibrillator.
Results: We included 79 female AC patients (42% probands, age 42±16 years), of which 26 (33%) had experienced ventricular arrhythmia (Table). RV FAC was worse in women with than without ventricular arrhythmia. RVOT and RVD were markers of ventricular arrhythmia only as absolute values. LVEF did not differ between the groups.
Conclusions: RV FAC and absolute RV dimensions were markers of ventricular arrhythmia, while indexed dimensions were not. Evaluation of female AC patients should not rely on indexed values established in predominantly male studies. Further studies on imaging markers in female AC patients are warranted.