In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.

The free consultation period for this content is over.

It is now only available year-round to EACVI Silver Members, Fellows of the ESC and Young combined Members

Association of left atrial function echocardiographic parametres with fibrosis assesed invasively in patients with sinus rhythm and atrial fibrillation undergoing ablation for atrial fibrillation.

Session Poster session 2

Speaker Ewa Pilichowska

Event : EuroEcho 2016

  • Topic : imaging
  • Sub-topic : Imaging
  • Session type : Poster Session

Authors : E Pilichowska (Warsaw,PL), J Baran (Warsaw,PL), P Kulakowski (Warsaw,PL), B Zaborska (Warsaw,PL)

E Pilichowska1 , J Baran1 , P Kulakowski1 , B Zaborska1 , 1Grochowski Hospital, Postgraduate Medical School, Department of Cardiology - Warsaw - Poland ,

Clinical applications

European Heart Journal Supplements ( 2016 ) 17 ( Supplement 2 ), ii110

Electromorphological remodeling and fibrosis of the left atrium (LA) play important role in pathogenesis of atrial fibrillation (AF) and may predict poor catheter ablation (CA) outcome. LA fibrosis may be assessed invasively using electroanatomical mapping (EAM) during electrophysiological study. We have previously shown that the extent of LA fibrosis may be assessed non-invasively by specle tracking echocardiography (STE), however the effects of underlying cardiac rhythm (sinus or AF) on the accuracy of analysis have not yet been examined.
The aim was to assess the relationship between LA function derived from echocardiography (TTE) and LA fibrosis using EAM in patients with AF and sinus rhythm (SR).

Patients (pts) n=66 (64% males, mean age 56+/-10) with non-valvular AF treated with first CA were studied. LA volume using biplane area-length method was calculated. In STE global peak atrial longitudinal strain (PALS) was obtained by averaging values in all LA segments in 4- and 2-chamber views. E/E' and LA stiffness index - the ratio of E/E' to PALS were assessed.
The EAM of LA was build using Carto System before CA. Low amplitude potentials area (LAPA) was quantitatively analysed and expressed as a percentage of LA surface using the range 0.5-0.05 mV to detect potential sites of fibrosis.

48 (72%) pts were in SR, 18 (28%) pts in AF during the analysis. Pearson correlation analysis showed a significant correlation between LAPA and TTE parameters only in pts with SR not in AF subgroup (table).

Assessment of LA function by TTE with STE correlates well with the extent of LA fibrosis assessed by EAM only in SR. Thus, STE may be useful in non-invasive assessment of LA fibrosis and proper selection of candidates for CA in SR, but may not be applicable during AF rhythm. These preliminary findings warrant further examinations.

TTE parameters









PALS global





LA stiffness





E/E ’


< 0.001



LA volume





Get your access to resources

Join now
  • 1ESC Professional Members – access all ESC Congress resources 
  • 2ESC Association Members (Ivory, Silver, Gold) – access your Association’s resources
  • 3Under 40 or in training - with a Combined Membership, access all resources
Join now
logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are