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7-Tesla Cardiac MRI with vector-ECG gating despite the magnetohydrodynamic effect in healthy volunteers

Session Poster session 2

Speaker Christian Hamilton-Craig

Event : EuroCMR 2019

  • Topic : imaging
  • Sub-topic : Cardiac Magnetic Resonance: Physics and Technology
  • Session type : Poster Session

Authors : C Hamilton-Craig (Brisbane,AU), D Staeb (Brisbane,AU), K O'brien (Brisbane,AU), G Galloway (Brisbane,AU), M Barth (Brisbane,AU)

Authors:
C Hamilton-Craig1 , D Staeb1 , K O'brien2 , G Galloway3 , M Barth1 , 1University Of Queensland, Centre for Advanced Imaging - Brisbane - Australia , 2Siemens Healthineers - Brisbane - Australia , 3Translational Research Institute - Brisbane - Australia ,

Citation:
European Heart Journal - Cardiovascular Imaging ( 2019 ) 20 ( Supplement 2 ), ii326

Background: Ultra-high-field (B0 = 7 Tesla) cardiovascular magnetic resonance (CMR) offers increased resolution. However cardiac imaging requiring ECG gating is significantly impacted by the magneto-hydrodynamic (MHD) effect, which distorts the ECG trace. Previously, 7T CMR was often constrained to using pulse oximetry for triggering. We explored the technical feasbility of a 7T research MR scanner using of-the-art ECG trigger algorithm to assess left and right ventricular volumes, aortic and pulmonary valve flow.

Methods: 7T CMR scans were performed on 10 healthy volunteers on whole-body research MRI scanner (Siemens Healthcare, Erlangen, Germany) with 8 channel Tx/32 channel Rx cardiac coil (MRI Tools GmbH, Berlin, Germany) under institutional review board approval. Vectorcardiogram ECG was successfully performed using a learning phase outside of the magnetic field, with a trigger algorithm with sufficient accuracy for CMR despite severe ECG signal distortions from the 7T field. Cine CMR was performed after 3rd-order B0 shimming using a high-resolution breath-held ECG-retro-gated segmented two-dimensional spoiled gradient echo sequence, and 2-dimensional phase contrast flow imaging. Analysis was performed using CMR42 software (Circle CVi, Calgary).

Results: Successful 7T CMR scans were acquired in all patients (100%) using the Vectorcardiogram 3-lead ECG method. Image quality was sufficient to quantitate both left and right ventricular volumes, ejection fraction, aortic and pulmonary blood flow and regurgitant fractions in 9/10 (90%) of volunteers (figure 1), with one volunteer having difficulty with breath-holding and ventricular ectopy causing gating artefacts. Conclusion: Reliable cardiac ECG triggering is feasible in healthy volunteers at ultra-high field utilizing a state-of-the-art 3-lead trigger device despite signal distortion from the MHD effect, and provides sufficient image quality for quantitative analysis. Other ultra-high-field imaging applications such as human brain functional MRI with physiologic noise correction may benefit from this method of ECG triggering

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